BioBLU^® f Single-Use Bioreactors

BioBLU f Single-Use Vessels for microbial applications

BioBLU f Single-Use Bioreactors for fermentation applicationsFermentation vessel for microbiological applications from E. coli to yeast.

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BioBLU f Single-Use Bioreactors are rigid-walled stirred-tank bioreactors specifically designed for robust microbial applications using bacteria, yeasts, and fungi. The scalable BioBLU f portfolio covers a working volume range of 65 mL – 3,75 L. The rigid wall stirred tank design mimics traditional bioreactors and supports effective mixing and mass transfer making them suitable for high-cell density fermentation.

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BioBLU Single-Use Bioreactors can help you increase efficiency and minimize process risks. Find out more!

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Applicazioni

Caratteristiche

The BioBLU Single-Use Bioreactors for microbial applications at a glance:

The rigid wall stirred tank design mimics traditional bioreactors and supports effective mixing and mass transfer making them suitable for high-cell density fermentation.
• BioBLU 0.3f (working volume 65 – 250 mL)
• BioBLU 1f (working volume 250 mL – 1,25 L)
• BioBLU 3f (working volume 1,25 L- 3,75 L)

The BioBLU Single-Use Bioreactors are compatible with the small and bench-scale bioprocess controllers from Eppendorf and selected third-party controllers.

Bioreactor body and head plate

• Stirred-tank design: The stirred-tank design offers reliability scalability and facilitates the easy replacement of traditional glass bioreactors.
• Equipment: BioBLU Single-Use Bioreactors are assembled with sparger, overlay, gas filters for inlet and exhaust as well as penetrations for pH, DO, and temperature sensors, liquid additions, sampling, and harvest. All head plate ports are clearly marked for ease of use. Spare Pg 13.5 ports can be equipped with single-use septa, tri-ports and compression fitting adaptors for more flexibility.
• Sterilization: BioBLU 0.3f and 1f Single-Use Bioreactors are delivered sterile. Irradiated by > 15 kGy (β) or > 25 kGy (X-ray). SAL-level 10^-6 for X-ray irradiated BioBLU^® Single-Use Bioreactors. The BioBLU 3f Single-Use Bioreactor is not presterilized and is autoclavable.

Suitable for high cell densities

BioBLU f Single-Use Bioreactors support the high mass transfer and heat removal requirements of fermentation processes.
• Motor: Powerful overhead drives enable high agitation speeds. Sealed magnetic drive with fully enclosed bearings maintain vessel sterility.
• Baffles: Interior baffles aid mixing and mass transfer. The baffles of the BioBLU 1f additionally provide efficient heat removal through active cooling.
• Impellers: Multiple Rushton-type impellers for efficient mixing and mass transfer.
• Cooling: Smart solutions for cooling using cooling baffles or cooling fingers.
• Exhaust treatment: Effective liquid-free exhaust condensation (Peltier), electric heater band or water-cooled exhaust treatment.